The purpose of this report is to further educate and to bring more attention to the drug 2C-I and how it affects a person's physical health.
Physical health is a vital part in an individual's life and if it is affected then it can lead to some serious health issues. With physical health being a huge part of surviving and maintaining a healthy lifestyle, it is extremely important to keep it at it’s best and healthy. If a person isn’t healthy and well then their day to day activities won't be at full capacity and when they are working it will affect their workplace in a negative way. If the workplace is being affected then it causes a rippling effect which may end up having their surrounding society affected. Physical health is very important to society because it is the key to a fulfilling life and lowering further risk of developing diseases. If a death from a disease occurs it will send the whole of the society into sorrow and distress.
This report will start with production elements and processes of how 2C-I is made and the chemical side of it. The chemical properties of 2C-I and how it will affect the body and the brain and to finish off how the 2C-I affects an individual's physical health.



Background

To make 2,5-dimethoxy-4-iodophenethylamine it starts with having phthalic anhydride and 2,5-dimethoxyphenethylamine heated up until they have been crystallized. Once crystallized it is to be dissolved and again crystallized to form N-(2-(2,5-dimethoxyphenyl)ethyl)phthalimide. N-(2-(2,5-dimethoxyphenyl)ethyl)phthalimide will now react to acetic acid and iodine monochloride which yields N-(2(2,5-dimethoxy-4-iodophenyl)ethyl)phthalimide. This will react with hydrazine hydrate and then it’ll be washed with a solution of hydrochloric acid and recrystallized forming the end product, being 2,5-dimethoxy-4-iodophenethylamine hydrochloride.

Figure 1: Chemical structure of 2,5-dimethoxy-4-iodophenethylamine retrieved from public domain  <https://commons.wikimedia.org/wiki/File:2C-I2DACS.svg> 

The chemical formula for 2C-I is C10H14INO2 and the molecular weight is 307.13 g/mol. The solubility for 2C-I is currently unknown as there hasn’t been thorough research on its specifics. After this whole process the crystallized version is crushed and made into one of three forms, straight powder, liquid or in a tablet. The most common form is powder as it is easier to choose how much the individual is willing to consume.

The way in which a person intakes 2C-I can differ on personal preference. It can be snorted and in which it goes through the nose and down the throat, injected which will enter the bloodstream via syringe and have a quicker reaction time as it is directly coming into contact with the body's internal organs. The last way of consuming 2C-I is via tablet and the way the tablet will start is after it is swallowed, the outer layer of the tablet will dissolve inside the consumer's stomach. 2C-i has been referred to as a mixture of LSD, ecstasy, bath salts and spice except it has a longer high and unpredictable effects. In the brain's defence it will act in ways including Nausea and vomiting, high blood pressure, Hyperventilation, Muscle spasms, Kidney failure, Seizures, Coma and worst case scenario Death. With 2C-I being a hallucinogen it greatly affects a person's vision creating unique sensations and visual impairments. Some users have stated that it gives them a warm and deep sense of hearing while listening to music.
As 2C-I is not a medically approved nor popular drug, there hasn't been any professional trials because it is a designer drug. In saying this it means that the drug can differ from each seller/producer this why the effects can be very unpredictable.    

Discussion

2C-I’s effects on an individual's physical health belongs all in the brain. With it being a psychoactive and hallucinogenic drug the brain will be largely in control on the individual's effects and reactions. Being a designer drug it can be very unpredictable and the effects may differ from person to person as everyone's mind thinks and reacts in different ways. The hallucinations may cause the person to act in a way of causing self harm over and over again which can be as deadly as smashing their head against a wall till they develop brain injuries.
The brain is the center of all decisions and if it is affected by 2C-I then the brain won’t be able to make smart and mature decisions. 2C-I will affect an individual's vision and with the long lasting high the person will likely undertake the challenge of driving. While driving the person's vision will be vastly out of the normal, with still objects being able to move and in some cases the world around them will feel small and confined. This can lead to serious injury, it can cause them to either crash and cause harm to themselves or to harm those around them.
The abuse of 2C-I can be fatal, it can lead to the user being dependent of the drug and constantly needing it. This affects the user heavily and it can affect his or hers physical health immensely. It can lead to a lack of key components, which will have the individual lean towards poor choices. Unhealthy food can be an easy and harmful health issue as it can cause serious long term health problems including obesity, diabetes, heart attacks and internal organ problems. Their ability to prioritize their daily activities will become harder, with their mind being manipulated and affected by the drug. They will be mainly focused on 2C-I and all other priorities can be misplaced. The individual can withdraw themselves from their social life. All of these key components are necessary for someone to be physically happy and healthy. 2C-I is a drug of dependence meaning it is easy for the user to become addicted, this can cause the effects to be a recurring event. 
If an individual abuses or overdoses on the drug 2C-I it can affect their physical health in many ways. It can largely affect how the person perceives what is going on around them, which can be harmful to both the user and those around. The side effects and main effects can increase the risk of a decline in physical health and wellbeing.        

Conclusion

In conclusion this report has provided key information on how 2C-I affects an individual's physical health and all the side effects that can come with it. It has given the chemical properties used in the process of making 2C-I. Explored how it reacts inside the person's body and what the defence mechanisms are from the brain. The report has also given a brief understanding on how 2C-I will affect an individual's physical health both long term and short term. 2C-I can be very harmful to not only the consumer but the people around them. If a person isn’t in the right of mind the effects of the drug can be fatal, causing them to do unpredictable things. 2C-I has a huge effect on both the brain and body much similar with physical health. Therefore, 2C-I can have a huge impact on one’s physical health.    

Public Education Piece

For my public education piece I have made an awareness poster. 

References

Biervrienden. (2013). Drugtest: 2C-I with English Subtitles | Retrieved from
 <https://www.youtube.com/watch?v=jk5EMTo1hDE> 
Endologik. (Mar 21, 2004). 2C-I Trip Reports. Retrieved from <https://drugs-forum.com/threads/2c-i-trip-reports.5963/>
PsychonautWiki. (n.d). 2C-I. Retrieved from <https://psychonautwiki.org/wiki/2C-I>
Newport Academy. (2012). Abuse of the drug smiles. Retrieved from <https://www.newportacademy.com/resources/substance-abuse/smiles-abuse/>
Smiles drug. (2012). Smiles drug. Retrieved from <http://www.smilesdrug.com>
Testa, J. (2012, September, 29). Everything You Need To Know About The Designer Drug Known As "Smiles." Buzzfeed. Retrieved from 
<https://www.buzzfeed.com/jtes/everything-you-need-to-know-about-smiles?utm_term=.olPZ814Y6#.ds6anw2r7> 
Erowid online books. (2015). Pihkal. Retrieved from
<https://erowid.org/library/books_online/pihkal/pihkal033.shtml> 
Scientific working group for the analysis of seized drugs. (2005 22 August). 2,5-DIMETHOXY-4-IODOPHENETHYLAMINE. Retrieved from    
<http://www.chemspider.com/Chemical-Structure.23254626.html 
http://www.swgdrug.org/Monographs/2,5-DIMETHOXY-4-IODOPHENETHYLAMINE.pdf>